Adrenal-18

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Topic: Adrenal-18.

Posted on: November 24, 2016

Patient no 5
A 29 years old female presented with complaints of fatigue, lethargy and frequent thirst. She
has been having episodes of hypotension as well. Her BMI is 23 kg/m2 . Pigmentation is seen in
the palmar creases and the buccal mucosa She has a small diffuse goiter.

• Her lab investigations are as follows:
• Plasma Glucose fasting: 15.3 mmol/L
• Serum Na: 123 mmol/L
• Serum K: 6.0 mmol/L
• Serum Ca: 2.38 mmol/L (2.10-2.65)
• Serum Cortisol (0800 h): 2 (10-25 ng/ml)
• Plasma ACTH (0800 h): 1650 pg/mL(10-50)
• Serum TSH: 38 m IU/L (0.4-4.5)

a. What is the most likely diagnosis?

b. Name TWO hormones you will like to test in this patient

a. Polyglandular autoimmune syndrome type II
(Schmidt Syndrome)

b. FSH and LH
Causes of Primary Adrenal Insufficiency
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