Liver-3

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Topic: Liver-3

Posted on: November 24, 2016

Patient no 7

A 42 year old female presented with jaundice, fatigue and intense pruritus, for the last 6
months. Her biochemical profile is as following:

• Bilirubin: 340 μmol/L (0-17)
• Serum total proteins: 86 g/L (65-80)
• Albumin: 31 g/L (35-50)
• ALP: 540 U/L (45-135)
• AST: 93 U/L (<42)
• GGT: 234 U/L (<38)
• Cholesterol: 7.6 mmol/L
• Viral markers: Negative
• Antimitochondrial antibodies: Positive
• What is the most probable diagnosis?
• Name ONE lipid fraction which will be most markedly raised in this patient?

1. Primary Biliary Cirrhosis
2. Lipoprotein X

Ref No 7
Clinical manifestations, diagnosis, and natural history of primary biliary cirrhosis
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