Male reproductive system-1

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Topic: Male reproductive system-1

Posted on: November 24, 2016

Patient no 3
A 26 years old male is being investigated for infertility along with his female partner.
He has azoospermia on semen analysis. His hormonal profile shows:

• Serum Testosterone: 987 ng/dl (260-1000)
• Serum LH: 14 mIU/ml (1-8)
• Androgen Insensitivity Index: 13,818 (<2000)
• Serum FSH: 5.2 mIU/ml (1-6)
• Prolactin: 9.7 ng/ml (5-20)
• What is the most probable diagnosis
• Name ONE genetic test which can be very helpful in confirming the diagnosis.

1. Mild Androgen Insensitivity Syndrome
2. Androgen receptor gene defect

Ref No 3
Angeliki Galani, Sophia Kitsiou-Tzeli, Christalena Sofokleous, Emmanuel
Kanavakis, Ariadni Kalpini-Mavrou
Androgen insensitivity syndrome: clinical features and molecular defects
HORMONES 2008, 7(3):217-229

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